Flow cytometric immunophenotyping in fine-needle aspiration of lymph nodes

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Flow cytometric immunophenotyping in fine-needle aspiration of lymph nodes.

Fine-needle aspiration (FNA) of lymph nodes has been regarded as a useful method in the diagnosis of lymphadenopathy. However, this procedure has been shown to be of limited value in the diagnosis of low or intermediate grade malignant lymphomas in some studies. Immunophenotyping is an essential adjunct to cytomorphology for the diagnosis of lymphoma by FNA. Immunophenotyping using flow cytomet...

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Needle aspiration of lymph nodes was used at the beginning of the 20th century to identify parasites in sleeping sickness, secondary syphilis, filariasis, and bubonic plague. In 1921, Guthrie at the Johns Hopkins Hospital described systematic diagnosis of lymph node aspirates using air dried films and Romanowsky staining. This began the modern development of this technique and I intend to summa...

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Fine Needle Aspiration Biopsy of Lymph Nodes

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Flow cytometry immunophenotyping (FCI) has an important role in the clinic work-up of fine needle aspirates (FNAs) of lymph nodes. Its standardization has been defined by proposed analytical protocols and procedures used to assure proper analytical results also in those non-routine samples. In Institute of Clinical Chemistry, "Merkur" University Hospital, FCI is accredited method according to l...

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ژورنال

عنوان ژورنال: Journal of Korean Medical Science

سال: 1999

ISSN: 1011-8934,1598-6357

DOI: 10.3346/jkms.1999.14.4.393